Genesis®200 is the world’s first quantitative, fully-automated, stain-free, multi-organ, 2D & 3D multiphoton imaging system, designed to aid in preclinical studies as well as clinical trials for the drug development of Nonalcoholic Steatohepatitis (NASH).
HistoHepa© is a suite of image analysis tools that are designed to generate objective and highly accurate quantification so as to enhance the assessment and diagnosis of liver diseases.
100 collagen features in the overall, central vein, portal tract, and perisinusoidal regions are quantified on a continuous scale.
Tailored for NASH assessment, these measurements quantify up to 275 features with qFibrosis, qInflammation, qBallooning, and qSteatosis.
Changes of Collagen Proportional Area (CPA) with NASH CRN stages at baseline of study
Changes of qFibrosis Index with NASH CRN stages at baseline of study
qFibrosis provides more definitive results and reduction in the No Change category.
Characterizes and quantifies collagen fibers unobservable with conventional stains.
Quantifies fat measurements and monitors steatosis development.
Detects and quantifies the area, number and density of ballooned cells.
Distinguishes and quantifies portal as well as lobular inflammation.
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