EASL 2024
Breakfast Meeting
5th Jun 2024
8 – 10am CEST
8 – 10am CEST
Stay up-to-date with the latest research
This year, our Breakfast Meeting at EASL will focus on the cutting-edge advances in AI digital pathology in MASH and MASLD clinical trials. We have an exciting lineup of presentations and an interactive session with expert panelists, who will share their insights and experiences into management of MASH patients and future clinical trial design in the post-drug approval era.
Attendees will have the opportunity to:
- Learn about the latest AI digital pathology tools for the assessment of pharmacodynamic responses in liver biopsies during MASH clinical trials
- Understand how we can use measures of spatial-based morphology and features of fibrosis that correlate to patients’ clinical outcomes
- Engage in a thought-provoking panel discussion on the role of liver biopsies in clinical practice and future trials in MASH post-drug approval
Moderated by
Nikolai Naoumov
MD, PhD, FRCP, FRCPath, FAASLD
Professor of Hepatology
Royal College of Physicians (London)
Event Speakers
Arun Sanyal
MD
Professor of Medicine and Director at
VCU Stravitz-Sanyal Institute for Liver Disease and Metabolic Health
Jonathan Fallowfield
BSc (Hons), BM (Hons), PhD
Personal Chair of Translational Liver Research at University of Edinburgh
Timothy Kendall
BM, PhD, FRCPath
Senior Clinical Fellow in Pathology & Honorary Consultant Histopathologist at University of Edinburgh
Dean Tai
PhD
Co-founder and Chief Scientific Officer at HistoIndex
Highlights from 2023 AASLD
Accepted presentations
Identification and validation of pre-identified morphological baseline features for prediction of fibrosis progression in MAESTRO-NASH
Time and Location: Friday, 7 June, 5:15 – 5:30 PM, Gold Room
Presenter: Dr. Jörn M Schattenberg
Presentation ID: OS-124
Stain-free digital pathology imaging provides microarchitecturally-resolved insights into scar evolution allowing direct clinical outcome prediction in MASLD
Time and Location: Friday, 7 June, 5:45 – 6:00 PM, Space 1+2
Presenter: Dr. Timothy Kendall
Presentation ID: OS-087
Time and Location: Friday, 7 June, 5:15 – 5:30 PM, Gold Room
Presenter: Dr. Jörn M Schattenberg
Presentation ID: OS-124
Stain-free digital pathology imaging provides microarchitecturally-resolved insights into scar evolution allowing direct clinical outcome prediction in MASLD
Time and Location: Friday, 7 June, 5:45 – 6:00 PM, Space 1+2
Presenter: Dr. Timothy Kendall
Presentation ID: OS-087
Poster Tour
qBallooning: AI-based ballooned hepatocyte detection and quantification by second harmonic generation/two photon excitation microscopy
Time and Location: Saturday, 8 June, 12:15 AM – 12:22 PM, Track Hub: Metabolism, Alcohol & Toxicity
Presenter: Dr. Dean Tai
Poster Number: FRI-208
Poster Presentations
Assessment of fibrosis change rates in placebo arm of metabolic dysfunction-associated steatohepatitis drug trials based on pathologist readouts and qFibrosis continuous values
Time and Location: Wednesday, 5 June, Poster Area
Poster Number: WED-213
AI digital pathology unmasked the “No Change” in conventional pathological assessment of MASLD patients with one year lifestyle intervention in a prospective cohort study
Time and Location: Wednesday, 5 June, Poster Area
Poster Number: WED-319
Validation of optimal liver biopsy size for reliable quantitation of fibrosis severity in different areas and structures of liver lobule using second harmonic generation microscopy with artificial intelligence analyses
Time and Location: Friday, 7 June, Poster Area
Poster Number: FRI-203
Regional fibrosis progression analysed by digital pathology with artificial intelligence is associated with renal dysfunction
Time and Location: Friday, 7 June, Poster Area
Poster Number: FRI-267
Genetic determinants of disease progression in metabolic dysfunction-associated liver disease patients unresponsive to lifestyle intervention: implications for personalized medicine
Time and Location: Friday, 7 June, Poster Area
Poster Number: TOP-310
qBallooning: AI-based ballooned hepatocyte detection and quantification by second harmonic generation/two photon excitation microscopy
Time and Location: Saturday, 8 June, 12:15 AM – 12:22 PM, Track Hub: Metabolism, Alcohol & Toxicity
Presenter: Dr. Dean Tai
Poster Number: FRI-208
Poster Presentations
Assessment of fibrosis change rates in placebo arm of metabolic dysfunction-associated steatohepatitis drug trials based on pathologist readouts and qFibrosis continuous values
Time and Location: Wednesday, 5 June, Poster Area
Poster Number: WED-213
AI digital pathology unmasked the “No Change” in conventional pathological assessment of MASLD patients with one year lifestyle intervention in a prospective cohort study
Time and Location: Wednesday, 5 June, Poster Area
Poster Number: WED-319
Validation of optimal liver biopsy size for reliable quantitation of fibrosis severity in different areas and structures of liver lobule using second harmonic generation microscopy with artificial intelligence analyses
Time and Location: Friday, 7 June, Poster Area
Poster Number: FRI-203
Regional fibrosis progression analysed by digital pathology with artificial intelligence is associated with renal dysfunction
Time and Location: Friday, 7 June, Poster Area
Poster Number: FRI-267
Genetic determinants of disease progression in metabolic dysfunction-associated liver disease patients unresponsive to lifestyle intervention: implications for personalized medicine
Time and Location: Friday, 7 June, Poster Area
Poster Number: TOP-310